THE UNIVERSITY OF BRITISH COLUMBIA
RESEARCH IN ASTHMA
International severe asthma registry (ISAR): protocol for a global registry
The International Severe Asthma Registry (ISAR) is a collaborative initiative comprising existing and new registries that builds on data from multiple nations and regions and increases the statistical power and comparability of data. It is the first global...
The International Severe Asthma Registry (ISAR) is a collaborative initiative comprising existing and new registries that builds...
Does the occurrence of a severe asthma exacerbation change the rate of subsequent events?
Does the occurrence of a severe asthma exacerbation affect the rate of subsequent events? To the best of our knowledge, this important question has not been evaluated in asthma. Conventional wisdom is that previous history of asthma exacerbations is the be...
Does the occurrence of a severe asthma exacerbation affect the rate of subsequent events? To the best of our knowledge, this imp...
The cost-effectiveness of as-needed budesonide/formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in the UK
Respiratory Medicine, 2020 (171); 106079
Cost-effectiveness of Implementing Objective Diagnostic Verification of Asthma in the United States
J Allergy Clin Immunol. 2019;S0091-6749(19)31634-3
Stability of asthma symptom control in a longitudinal study of mild–moderate asthmatics
J Allergy Clin Immunol Pract. 2017 Nov - Dec;5(6):1663-1670.e5
Complementary and alternative asthma treatments and their association with asthma control: a population-based study
BMJ Open. 2013 Sep 4;3(9):e003360
History of Asthma in Patients with Chronic Obstructive Pulmonary Disease: A Comparative Study of Economic Burden.
Ann Am Thorac Soc. 2016 Feb;13(2):188-96
The preventable burden of productivity loss due to suboptimal asthma control: a population-based study
Chest. 2014 Apr;145(4):787-793
The impact of comorbidities on productivity loss in asthma patients
Respir Res. 2016 Aug 26;17(1):106
Long-term effects of inhaled corticosteroids on bone mineral density in older women with asthma or COPD: a registry-based cohort study
Arch Osteoporos. 2018 Oct 29;13(1):116
A systematic review of the adverse events and economic impact associated with oral corticosteroids in asthma
J Asthma. 2019 Dec;56(12):1334-1346
Asthma is not associated with the need for surgery in Crohn’s disease when controlling for smoking status: a population-based cohort study.
Clin Epidemiol. 2018 Jul 12;10:831-840
Cost-effectiveness of tiotropium versus omalizumab for uncontrolled allergic asthma in US
Cost Eff Resour Alloc. 2018 Jan 30;16:3
The importance of measuring asthma control in emerging economies.
Int J Tuberc Lung Dis. 2014 Mar;18(3):254
The projected economic and health burden of sub-optimal asthma control in Canada
Respir Med. 2018 May;138:7-12
Has asthma medication use caught up with the evidence? A 12-year population-based study of trends
Chest. 2017 Mar;151(3):612-618
Predictors of inappropriate usage of reliever medications in asthma: a 12-year population-based study
BMC Pulm Med. 2018 Feb 12;18(1):33.
Dispensation of long-acting β agonists with or without inhaled corticosteroids, and risk of asthma-related hospitalisation: a population-based study
Thorax. 2014 Apr;69(4):328-34
Comparative outcomes of leukotriene receptor antagonists and long-acting β-agonists as add-on therapy in asthmatic patients: a population-based study
J Allergy Clin Immunol. 2013 Jul;132(1):63-9
Influences of Socioeconomic Status on Costs of Asthma Under Universal Health Coverage
Med Care. 2016 Aug;54(8):789-95
Excess medical costs in patients with asthma and the role of comorbidity
Eur Respir J. 2016 Dec;48(6):1584-1592
Ten-year trends in direct costs of asthma: a population-based study
Allergy. 2017 Feb;72(2):291-299
Economic and health effect of full adherence to controller therapy in adults with uncontrolled asthma: A simulation study
J Allergy Clin Immunol. 2014 Oct;134(4):908-915.e3
The natural history of severe asthma and influences of early risk factors: a population-based cohort study
Thorax. 2016 Mar;71(3):267-75
Cost-effectiveness of bronchial thermoplasty, omalizumab, and standard therapy for moderate-to-severe allergic asthma
PLoS One. 2016 Jan 11;11(1):e0146003
The impact of inappropriate use of short acting beta agonists in asthma
Respir Med. 2017 Oct;131:135-140
One-year outcomes of inhaled controller therapies added to systemic corticosteroids after asthma-related hospital discharge
Respir Med. 2015 Mar;109(3):320-8
Post-hospital syndrome in adults with asthma: a case-crossover study
Allergy Asthma Clin Immunol. 2013 Dec 23;9(1):49
Costs and health outcomes associated with primary versus secondary care after an asthma-related hospitalization, a population-based study
Chest. 2013 Aug;144(2):428-435
Less chaos in the prognosis of asthma-chronic obstructive lung disease overlap.
Lancet Respir Med. 2016 Jun;4(6):421-2
The projected economic and health burden of uncontrolled asthma in the United States
Am J Respir Crit Care Med. 2019 Nov 1;200(9):1102-111
The economic burden of multimorbidity in severe asthma patients: a 20-year population-based study
Thorax. 2019 Dec;74(12):1113-1119
Asthma control and productivity loss in those with work-related asthma: a population-based study
The objectives of this study were to evaluate the associations between 1) asthma control and work-related asthma (WRA), 2) productivity loss and WRA/NWRA status and 3) productivity loss and WRA/non-work-related asthma (NWRA) status in individuals with the...
The objectives of this study were to evaluate the associations between 1) asthma control and work-related asthma (WRA), 2) produ...
Saving in medical costs by achieving guideline-based asthma symptom control: a population-based study
This study aimed at informing an evidence gap in the literature. We have used a prospectively recruited sample, longitudinal evaluation of costs and control, and updated definitions of asthma control (according to the Global Initiative for Asthma [GINA] 20...
This study aimed at informing an evidence gap in the literature. We have used a prospectively recruited sample, longitudinal eva...
Empowering pharmacists in asthma management through interactive SMS (EmPhAsIS): study protocol for a randomized controlled trial.
Previous studies have evaluated communication technologies in asthma care , but none of these studies have involved pharmacists.On the other hand, pharmacist-based studies on improving the management of asthma have hitherto used interventions whose real-wo...
Previous studies have evaluated communication technologies in asthma care , but none of these studies have involved pharmacists....
The additional burden of comorbidity along with asthma control on health-related quality of life in asthma
Using a longitudinal random sample of adults with asthma, we explored the performance of both generic and asthma-specific HRQoL instruments to simultaneously distinguish between different levels of asthma control and changes in comorbidity status. Our prim...
Using a longitudinal random sample of adults with asthma, we explored the performance of both generic and asthma-specific HRQoL...
Quality of life and asthma symptom control: room for improvement in care and measurement
The primary objective of this study was to quantify the gain in quality of life that can be achieved by achieving Global Initiative for Asthma (GINA) symptom control in patients with symptomatically uncontrolled or partially controlled asthma. We pursued s...
The primary objective of this study was to quantify the gain in quality of life that can be achieved by achieving Global Initiat...
Interaction effect of psychological distress and asthma control on productivity loss in patients with asthma: a population-based study
The emphasis of asthma management is focussed on achieving current symptom control and the prevention of future risk. From this perspective, it is much more relevant to evaluate the interaction of asthma control and psychological distress (PD) in determini...
The emphasis of asthma management is focussed on achieving current symptom control and the prevention of future risk. From this...
The added effect of comorbidity on health-related quality of life in patients with asthma.
Triple therapy in a single inhaler: a new option for uncontrolled asthma
Commentary on Virchow et al. (Lancet. 2019, https://doi.org/10.1016/S0140-6736(19)32215-9)
Long-Term Trajectories of Mild Asthma in Adulthood and Risk Factors of Progression
Using administrative health data from a large province in Canada, we aimed to examine the long-term trajectory of mild asthma in adults older than 16 years and to identify demographic, clinical, and treatment-related factors during the earlier stages of di...
Using administrative health data from a large province in Canada, we aimed to examine the long-term trajectory of mild asthma in...
Extent, trends, and determinants of controller/reliever balance in mild asthma: a 14-year population-based study
Understanding the current status of medication use in mild asthma will help illuminate the potential benefit of the permeation of new recommendations on the earlier use of controller therapies. Accordingly, the purpose of the present study was to document...
Understanding the current status of medication use in mild asthma will help illuminate the potential benefit of the permeation o...
Trends in systemic corticosteroids use in severe asthma: a 14-year population-based study
Population-based databases are uniquely positioned to provide robust estimates of the extent and trends of OCS use. Such databases are not affected by the self-selection of individuals into private insurance plans, or the strict inclusion criteria of patie...
Population-based databases are uniquely positioned to provide robust estimates of the extent and trends of OCS use. Such databas...
The costs of misdiagnosed asthma in a longitudinal study of the general population
We used a longitudinal population-based cohort of individuals with physician-diagnosed asthma to compare total direct asthma-related healthcare costs in patients with a confirmed diagnosis of asthma versus patients in whom a diagnosis of asthma was ruled o...
We used a longitudinal population-based cohort of individuals with physician-diagnosed asthma to compare total direct asthma-rel...
Direct health care costs associated with asthma in British Columbia.
The total health care costs of asthma are likely substantial because it is so common. Surprisingly, there has been no systematic assessment of health care costs associated with asthma care in Canada since the early 1990s. The objective of the present study...
The total health care costs of asthma are likely substantial because it is so common. Surprisingly, there has been no systematic...
Trends in asthma-related direct medical costs from 2002 to 2007 in British Columbia, Canada: a population based-cohort study.
The purpose of this population-based cohort study was to use BC administrative data to: 1) calculate the direct medical costs attributable to asthma in BC for the years 2002–2007; 2) evaluate asthma-related costs according to the level of asthma control; a...
The purpose of this population-based cohort study was to use BC administrative data to: 1) calculate the direct medical costs at...
Improving precision in the prediction of asthma exacerbations.
The global economic burden of asthma and chronic obstructive pulmonary disease
Int J Tuberc Lung Dis. 2016 Jan;20(1):11-23
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A parametric mixture model to characterize rate, duration and severity of exacerbations
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