THE UNIVERSITY OF BRITISH COLUMBIA
Research Specific Projects
EVALUATION PLATFORM IN COPD (EPIC)
ABOUT:
EPIC is a comprehensive decision-analytic simulation model for chronic obstructive pulmonary disease (COPD) that incorporates population demographics, risk factors (e.g. smoking), lung function, symptoms, and disease progression. EPIC is a Discrete Event Simulation (DES) model following individuals from birth to death (as well as immigration/emigration). As individuals progress through the model, their simulated quality of life, costs, and epidemiologic measures of lung diseases will be collected. The model can be used as a generic, standardized, and validated paradigm to project the burden of respiratory diseases in the future and to estimate the cost, effectiveness, and budget impact of competing health technologies.
The EPIC model looks at how policy decisions could minimize the impact of Chronic Obstructive Pulmonary Disease (COPD). In 2 minutes, learn the basics of the EPIC model: The EPIC Model in 2 Minutes
Principal investigator Mohsen Sadatsafavi discusses EPIC and ideas about decision analytic modelling with Stephanie Harvard: Mohsen Sadatsafavi on the EPIC Model
EPIC is an open-source model, and is publicly available as an R package through GitHub.
EPIC is accessible through the PRISM clould platform of the Peer Models Network. For more information, please refer to the Peer Models Network home page.
A MACRO-enalbed Excel Spreadsheet for EPIC can be downloaded from the Peer Models Repository.
Please cite:
Sadatsafavi, M., Ghanbarian, S., Adibi, A., Johnson, K., Mark FitzGerald, J., Flanagan, W., … Sin, D. (2019). Development and Validation of the Evaluation Platform in COPD (EPIC): A Population-Based Outcomes Model of COPD for Canada. Medical Decision Making. https://doi.org/10.1177/0272989X18824098
PARTNERS:
PUBLICATIONS:
Development and validation of the Evaluation Platform In COPD (EPIC): a population-based outcomes model of COPD for Canada
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Cost-Effectiveness of Case Detection Strategies for the Early Detection of COPD
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Development and validation of the Evaluation Platform In COPD (EPIC): a population-based outcomes model of COPD for Canada
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Cost-Effectiveness of Case Detection Strategies for the Early Detection of COPD
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Individualized prediction of lung-function decline in chronic obstructive pulmonary disease
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Characterizing undiagnosed chronic obstructive pulmonary disease: a systematic review and meta-analysis
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Heterogeneity in the respiratory symptoms of patients with mild-moderate COPD
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The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology.
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